Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus

Table 5

Genotype distribution of SIRT1 tag SNPs between CHD and control groups in smokers.

SNP	Genotype	CHD group (%)	Control group (%)	OR (95% CI)		OR’ (95% CI’)
rs3818292	G/A + A/A	135 (96.4)	60 (90.9)	2.700(0.793–9.193)	0.112	4.535(1.186–17.343)	0.027
	G/G	5 (3.6)	6 (9.1)	1
rs3818291	G/A + A/A	39 (26.9)	9 (13.6)	2.33(1.054–5.15)	0.037	3.035(1.283–7.18)	0.011
	G/G	106 (73.1)	57 (86.4)	1

, , or ; , , and were determined after adjusting for age, sex, smoking status, and HDL-c determined by logistic regression analysis.