GDF-15 Is Associated with Poor Physical Function in Prefrail Older Adults with Diabetes

Table 2

Association of GDF-15 tertiles with diabetes and physical function.

Diabetes	Poor physical function		GDF tertiles; (%)			Tertile 2 vs. Tertile 1		Tertile 3 vs. Tertile 1
			Tertile 1	Tertile 2	Tertile 3
						Unadjusted	Adjusted^#	Unadjusted	Adjusted^#
						OR (95% CI) value	OR (95% CI) value	OR (95% CI) value	OR (95% CI) value
No	No	19	13 (68.4)	3 (15.8)	3 (15.8)	Reference
No	Yes	45	14 (31.1)	21 (46.7)	10 (22.2)	6.5; (1.6-27.1)	4.7; (0.9-25.2)	3.1; (0.7-13.8)	1.8; (0.3-11.1)
Yes	No	11	2 (18.2)	5 (45.5)	4 (36.4)	10.8; (1.4-85.4)	12.7; (1.1-143.7)	8.7; (1.05-71.6)	9.6; (0.6-141.5)
Yes	Yes	33	6 (18.2)	7 (21.2)	20 (60.6)	5.1; (0.96-26.7); 0.056	2.8; (0.4-19.5)	14.4; (3.1-68.2)	9.7; (1.4-67.7)

#Adjusted for age, years of education, BMI, RAPA, total MNA-SF score, IL-6 tertiles, and TNF-α tertiles. Values are (%).