Rosa laevigata Michx. Polysaccharide Ameliorates Diabetic Nephropathy in Mice through Inhibiting Ferroptosis and PI3K/AKT Pathway-Mediated Apoptosis and Modulating Tryptophan Metabolism

Figure 3

RLP alters the metabolites of the kidney in DN mice. To evaluate the effects of RLP on DN mice, multivariate statistical analysis and pathway analysis were conducted. (a) Score plots of PCA showed the difference among control, model, and RLP groups. (b–e) Score plots and permutation tests of PLS-DA were performed to compare the control and model groups (b, c) as well as the model and RLP groups (d, e).

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