Research Article
Inulin Reduces Kidney Damage in Type 2 Diabetic Mice by Decreasing Inflammation and Serum Metabolomics
Table 3
Potential differential metabolites between the NC group and the DM group.
| Metabolites | Formula | HMDB | m/z | Retention time (min) | Change |
| Uridine | C9H12N2O6 | HMDB00296 | 243.06 | 1.75 | ↑ | Vitamin K2 | C41H56O2 | HMDB30017 | 625.42 | 9.85 | ↑ | L-Acetylcarnitine | C9H17NO4 | HMDB00201 | 202.11 | 4.33 | ↑ | Prostaglandin F1a | C20H36O5 | HMDB02685 | 377.23 | 4.94 | ↑ | L-Palmitoylcarnitine | C23H45NO4 | HMDB00222 | 436.28 | 6.25 | ↑ | 5-Hydroxy-N-formylkynurenine | C11H12N2O5 | HMDB04086 | 287.05 | 1.93 | ↑ | Prostaglandin H2 | C20H32O5 | HMDB01381 | 351.22 | 4.94 | ↑ | dUMP | C9H13N2O8P | HMDB01409 | 307.03 | 1.3 | ↓ | Leukotriene A4 | C20H30O3 | HMDB01337 | 317.21 | 6.05 | ↑ | Gamma-tocotrienol | C28H42O2 | HMDB12958 | 409.31 | 6.57 | ↓ | Phosphatidylcholine (20:4(5Z,8Z,11Z,14Z)/18:0) | C46H84NO8P | HMDB08431 | 854.59 | 23.43 | ↓ | Taurocholic acid | C26H45NO7S | HMDB00036 | 514.28 | 4.7 | ↑ | GlcCer (d18:1/16:0) | C40H77NO8 | HMDB04971 | 736.52 | 21.72 | ↓ | Phosphatidyl ethanolamine (20:2(11Z,14Z)/16:1(9Z)) | C41H76NO8P | HMDB09287 | 786.53 | 6.18 | ↓ | Deoxythymidine diphosphate-l-rhamnose | C16H26N2O15P2 | HMDB06354 | 529.06 | 4.49 | ↑ | Pyridoxine -phosphate | C8H12NO6P | HMDB01319 | 497.07 | 4.27 | ↑ | L-Tryptophan | C11H12N2O2 | HMDB00929 | 453.18 | 5.06 | ↑ | L-Carnitine | C7H15NO3 | HMDB00062 | 381.23 | 5.39 | ↑ | Phosphatidylcholine (16:0/0:0) | C24H50NO7P | HMDB10382 | 530.3 | 6.62 | ↓ | Allodeoxycholic acid | C24H40O4 | HMDB00478 | 391.28 | 5.69 | ↑ | Xanthosine | C10H12N4O6 | HMDB00299 | 283.07 | 2.16 | ↑ | Alpha-lactose | C12H22O11 | HMDB00186 | 377.09 | 0.92 | ↑ | 3a,7a-Dihydroxy-5b-cholestane | C27H48O2 | HMDB06893 | 449.36 | 22 | ↑ | Glycochenodeoxycholic acid 3-glucuronide | C32H51NO11 | HMDB02579 | 660.31 | 5.29 | ↑ | L-Lactic acid | C3H6O3 | HMDB00190 | 89.02 | 1.28 | ↓ | Retinyl ester | C20H30O2 | HMDB03598 | 301.22 | 5.46 | ↑ |
|
|