SLC25A28 Overexpression Promotes Adipogenesis by Reducing ATGL

Figure 2

The overexpression of SLC25A28 reduced glucose clearance efficiency when following a HFD. (a) IpGTT in mice with 12 weeks of HFD (; for each group; ANOVA, ). (b) Bar graphs are the AUC of ipGTT calculated from the original graph (; for each group; -test, ). (c) Fasting blood glucose concentration was measured after feeding for 12 weeks of HFD (; for each group; -test, ). (d) Plasma ATGL activity was measured by Elisa kit (; for each group; -test). (e) Plasma TC, TG, HDL-C, and LDL-C were measured (; for each group; -test, ). (f) Plasma free glycerol levels in plasma were measured (; for each group; -test, ). Ad-SLC25A28 versus Ad-GFP. AUC: the area under the curve; ATGL: adipose triglyceride lipase; FFA: free fatty acids; IpGTT: intraperitoneal glucose tolerance test; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.

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