Research Article
First Identification of Reinfection by a Genetically Different Variant of SARS-CoV-2 in a Homeless Person from the Metropolitan Area of Santiago, Chile
Figure 1
Genomic analysis of reinfected homeless patients. (a) Timeline shows the first (June 6th) and second (Aug 3rd) positive diagnosis by RT-qPCR for SARS-CoV-2. Nextstrain viral classification clade is shown for both samples. (b) RT-qPCR data using ORF1ab and RNase P (internal cellular control) probes for the homeless patient from nasopharyngeal swab sampling was obtained on June 6th (0606-201) and 58 days later, on August 3rd (0308-063). Cq-values are shown for ORFab (blue point) on the left and RNase P (pink line) on the right. (c) Clade structure of SARS-CoV-2 defined by Nexclade version 1.9.0 in Nextstrain classification: sample 0606-201 in clade 20B and 0308-063 in clade 20A. PANGO lineage classification by pangolin tool (0606-201; B.1 and 0308-063; B.1.1). (d) Genetic diversity plot of both pieces referred to the ancestral SARS-CoV genome. The highest diversity is present at ORF1b, ORF7a, S, and N.
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