Low-Dose Alcohol Improves Lipid Metabolism through Store-Operated Ca²⁺ Channel-Induced PPARγ Expression in Obese Mice

Figure 2

Low-dose alcohol consumption improved glucose tolerance and insulin sensitivity in obese mice. For IPGTT assay, mice were fasted for 12 h from 8 p.m. to 8 a.m. the next day. Mice were injected intraperitoneally with 2.5 g/kg glucose. (a) After baseline blood glucose levels were measured; blood glucose levels were measured at 15, 30, 60, and 120 min successively. (b) AUC was calculated according to IPGTT assay. For IPITT assay, the mice were injected intraperitoneally with 0.8 U/kg insulin. (c) After baseline blood glucose levels were measured, blood glucose levels were measured at 15, 30, 60, and 120 min successively. (d) AUC was calculated according to IPITT assay. (e) Serum APN levels were measured in every group at the end of last week. n = 8 per group.  < 0.05 vs. ND group; ^# < 0.05 vs. HFD group.

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