Hesperidin Induced HePG-2 Cell Apoptosis through ROS-Mediated p53/Bcl-2/Bax and p-mTOR Signaling Pathways

<div>Activation of intracellular apoptotic signaling pathways by hesperidin in HepG-2 cells. (a) The expression level of p-mTOR, P53, Caspase-9, Bcl-2, and Bax in hesperidin treated HePG-2 cells. Through densitometry analysis, the number above the bands is determined to present the protein expression levels. (b) Bands were quantified by Image J and results are expressed as a percentage of control; <i>β</i>-actin was used as the loading control. 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Journal of Food Biochemistry

fig7

Figure 7

Figure 7: Hesperidin Induced HePG-2 Cell Apoptosis through ROS-Mediated p53/Bcl-2/Bax and p-mTOR Signaling Pathways 