In Vitro Assessment of Myorelaxant and Antispasmodic Effects of Stigmas, Tepals, and Leaves Hydroethanolic Extracts of Crocus sativus

Figure 6

Antispasmodic effect of TPL (3 mg/ml) on the contraction of rat jejunum preincubated with atropine (Atr), hexamethonium (HEX), methylene blue (MB), and L-NAME and then precontracted with KCl 25 mM (a) or preincubated with nifedipine and precontracted with CCh 10⁻⁶ M (b). TPL, hydroethanolic extract of tepals. . The difference was statistically significant compared to the control (KCl 25 mM or CCh). ##<0.01): the comparison made between the effect of the extracts without and with the preincubation by the inhibitors (mean ± SEM; n = 6).