In Vitro Assessment of Myorelaxant and Antispasmodic Effects of Stigmas, Tepals, and Leaves Hydroethanolic Extracts of Crocus sativus

Table 1

The IC₅₀ value of different hydroethanolic extracts of C. sativus in antispasmodic and myorelaxant effects.

Effect	IC50 (mg/ml)
	Antispasmodic effect		Myorelaxant effect
	CCh (10^−6 M)	KCl (25 mM)	Spontaneous contraction
TPL	1.05 ± 0.07	1.28 ± 0.13	1.36 ± 0.15
LV	1.89 ± 0.17^NS	2.63 ± 0.09^NS	5.08 ± 0.45^NS
STG	2.11 ± 0.35	2.33 ± 0.22	6.61 ± 1.5

STG, hydroethanolic extract of stigmas; TPL, hydroethanolic extract of tepals; LV, hydroethanolic extract of leaves; NS, not significant, ; . The comparison was made between the STG and the byproducts of saffron (TPL and LV) (mean ± SEM; n = 6). IC₅₀ = the concentration of samples that give 50% relaxant activity.