T-Fiber, A Highland Barley Fiber-Rich Powder, Alleviates Hyperglycemia and Improves Kidney Pathology in Db/db Mice

Figure 4

T-fiber improved kidney function and alleviated nephropathy in Db/db mice. (a) and (b) Kidney weight and index in each experimental group. (c) and (d) Urine output and urine protein of experimental animals. (e) and (f) Determination of the level of CRE and BUN in mice in each experimental group. (g) Histological observation of HE staining (h) representative photomicrographs images showed PAS staining of kidney sections. (i) Histological observation of Masson trichrome sections. The data were expressed as mean ± SEM and analyzed using one-way ANOVA followed by Dunnett’s t-test, ^#P < 0.05 vs CT, ^##P < 0.01 vs CT, ^### vs CT, vs. model, vs. model. N = 6–8/group. Scar bar = 400 μm.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)