Protective Activity of Alpha-Mangostin against UVB-Induced Injury in HaCaT Cells by Modulating the Ceramide and MAPK and NF-κB Signaling Pathways

Figure 4

α-MG inhibited the phosphorylation of MAPK pathway proteins. (a, e) After α-MG pretreatment and then UVB irradiation, JNK, P38 MAPK, ERK1/2, p-JNK, p-P38 MAPK, and p-ERK1/2 were detected by western blotting. (b, d, f, h) GAPDH as an internal control and the expression levels of JNK, P38 MAPK, ERK1/2, p-JNK, p-P38 MAPK, and p-ERK1/2 proteins were presented ( vs. the control group; and vs. the UV group; n = 3; C: control group; U: UV group; T: treatment group).

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