Flavonoids from Lophatherum gracile Brongn. Ameliorate Liver Damages in High-Fat Diet and Streptozotocin-Induced Diabetic Mice by Regulating PI3K/AKT and NF-Kappa B Pathways

Figure 10

Effects of LGBF on the PI3K/AKT pathway and inflammation suppression in HFD and STZ-induced diabetic mice: (a) representative Western blot images of p-PI3K and p-AKT, (b) expression levels of p-PI3K with respect to β-actin, (c) expression levels of p-AKT with respect to β-actin, (d) representative Western blot images of p-P65 and IL-1β, (e) expression levels of p-P65 with respect to β-actin, and (f) expression levels of IL-1β with respect to β-actin. All experiments were repeated at least 3 times. The results are shown as mean ± SD. ^#, ^##, ^###, and ^#### versus the blank group. , , , and versus the model group.

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