Research Article
Efficacy for Bone Deterioration in Mice with Osteoporosis and Pharmaceutical Properties of a Novel Compound Calcium Carbonate Granule
Figure 1
The pharmaceutical advantage of CCCG. (a) Particle size distribution map of CCCG and CCD. (b) BET nitrogen adsorption desorption isotherm of CCCG and CCD. Comparison of calcium ion release rates from unground (c) or grounded. (d) CCCG and CCD granules. (e) Determination of vitamin D3 stability in vitro. Apparent permeability coefficients (Papp) of fluorescein sodium and calcium at different timing. (f) Papp of fluorescein sodium at different timing. (g) Papp of CCCG and CCD evaluated with calcium concentration. , and ; n = 3 or 4 per group.
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