The Effect of Lycium ruthenicum Murry Anthocyanins on the Apoptosis and Proliferation of H9c2 Cell Induced by Hypoxia

Figure 1

LRMA protected H9c2 cell viability reduction in hypoxia. H9c2 cells were exposed to LRMA (0, 12.5, 25, 50, and 100 μg/mL) for 0, 12, 24, 36, and 48 h in normoxia (a) or hypoxia for 24 h (b), respectively. Thereafter, the cell viability was analyzed. Next, followed by 50 μg/mL LRMA incubation for 24 h under hypoxic condition, LDH activity (c), morphological changes (d), and cell cycle distribution (e) of H9c2 cells were tested, respectively. N = 3. Different letters mean significant differences () while the same letter indicates no significant difference (). and . NS: no significance.