Network Pharmacology-Based Approach to Explore the Total Flavonoids of Phellinus igniarius against Hyperuricemia via Regulating the Nrf2/HO-1-ROS-ER Signaling Pathway

Figure 6

Impact of TFPI on the Keap1/Nrf2 signaling pathway and Nrf2 nuclear displacement in HK-2 cells. (a) Western blot and corresponding histograms of Keap 1, Nrf2, and HO-1 protein expression relative to β-actin. (b) Impact of TFPI on Nrf2 nuclear displacement in HK-2 cells. Data are means ± SD (n = 3).  < 0.01, compared with the control; ^## < 0.01, compared with the model.

(a)

(b)