Houttuynia cordata Polysaccharide Ameliorates Chronic Inflammation-Induced Intestinal Impairment by Zonula Occludens-1 in Rats

Figure 4

Effects of HCP on inflammation-associated cytokines and mediators in the small intestine. (a) Effect of HCP on NO secretion in small intestinal. (b) Effect of HCP on iNOS secretion in small intestinal. (c) Effect of HCP on tNOS secretion in small intestinal. (d) Effect of HCP on IL-1β secretion in small intestinal. Inflammatory mediators NO, iNOS, tNOS, and proinflammatory factor IL-1β were involved in the LPS-induced inflammatory cascade in the small intestinal, corresponding to the increase of related indexes in the LPS group. The therapeutic effect of HCP presented as decreased contents of NO, iNOS, tNOS, and IL-1β in small intestinal. ^#indicates significant difference compared with control group (), ^##indicates extremely significant difference compared with control group (); indicates significant difference compared with LPS group (), indicates extremely significant difference compared with LPS group ().

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