Effects and Mechanisms of Fucoxanthin from <i>Hizikia fusiforme</i> on Inhibiting Tongue Squamous Cell Carcinoma Proliferation via AKT/mTOR-Mediated Glycolysis

<div>Cell cycle distribution of fucoxanthin-treated CAL-27 cells. Data are presented as means ± SD (<i>n</i> = 3). (a) Sub-G1 peak (apoptotic peak) after treatment with 0, 3, 6, and 9 <i>μ</i>g/mL fucoxanthin for 24 h. The DNA content of cells in the G2 and M phases was twice that of cells in the G0 and G1 phases. Cells in the S phase exhibited a DNA content within the range of the aforementioned extremes. (b) Effect of fucoxanthin on cell cycle-related protein expressions of CAL-27 cells.</div>

Journal of Food Biochemistry

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Figure 4: Effects and Mechanisms of Fucoxanthin from <i>Hizikia fusiforme</i> on Inhibiting Tongue Squamous Cell Carcinoma Proliferation via AKT/mTOR-Mediated Glycolysis 

Figure 4 | Effects and Mechanisms of Fucoxanthin from Hizikia fusiforme on Inhibiting Tongue Squamous Cell Carcinoma Proliferation via AKT/mTOR-Mediated Glycolysis 