Astragaloside IV Suppresses the Effects of Hepatocellular Carcinoma Cells on Proliferation, Angiogenesis, and Invasion in Human Umbilical Vein Endothelial Cells by Controlling Exosomes by Inhibiting Rab27a

Figure 3

Exosomes derived from Hep3B and SK-Hep1 cells promote proliferation, angiogenesis, and invasion of HUVECs. (a) Proliferation, (b, d) invasion and (c, e) angiogenesis, and (f) E-cadherin and N-cadherin expression in HUVECs treated with Hep3B or SK-Hep1 cell-derived exosomes (50 and 100 μg/mL). Scale bar: 100 m. All data are expressed as the mean ± SD, n = 3.  < 0.05,  < 0.01,  < 0.001 vs. control.

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