Astragaloside IV Suppresses the Effects of Hepatocellular Carcinoma Cells on Proliferation, Angiogenesis, and Invasion in Human Umbilical Vein Endothelial Cells by Controlling Exosomes by Inhibiting Rab27a

Figure 6

AS-IV inhibits the effects of Hep3B cell-derived exosomes on tumor growth in vivo. (a) Tumor volume, (b, c) tumor weight, (d, e) Ki67 immunofluorescence staining, (f, g) CD34-labeled microvessels, and (h) E-cadherin and N-cadherin expression in xenograft tumors from various groups. Scale bar: 100 µm. All data are expressed as the mean ± SD, n = 3 or 5.  < 0.05,  < 0.01,  < 0.001 vs. control; ^# < 0.05, ^## < 0.01, ^### < 0.001 vs. Exo.

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