Research Article

Astragaloside IV-PESV Repressed T Cell Immunosuppression by Inhibiting PD-L1 Expression in Prostate Cancer through STAT3 Pathway

Table 1

The results of docking research.

LigandProteinBinding energies (kcal/mol)

Astragaloside IVSTAT3−8.3
PD-L1−9.5

PESV (LPDKVPIR peptide fragment)STAT3−5.9
PD-L1−5.2

PESV (VRDGYIADDK peptide fragment)STAT3−6.4
PD-L1−6.8