Hypoglycemic Effects of Inactivated Lactobacillus brevis YM 1301 on T2DM Mice

Figure 1

Effects of inactivated L. brevis YM1301 on glucose homeostasis and insulin sensitivity in the T2DM mice. (a) Inactivated L. brevis YM1301 reduced FBG in the T2DM mice. ^## NC vs. other groups; model vs. other groups; ^▽▽ before administration vs. after a 4-week treatment (n = 10). (b) Inactivated L. brevis YM1301 reduced GHb in the T2DM mice. ^## NC vs. model; model vs. treatment groups (n = 10). (c) Inactivated L. brevis YM1301 improved glucose tolerance in the T2DM mice. (d) AUC_OGTT. ^### NC vs. model; model vs. treatment groups (n = 10). (e) Inactivated L. brevis YM1301 improved insulin tolerance in the T2DM mice. (f) AUC_ITT. ^### NC vs. model; model vs. treatment groups (n = 10). (g) Inactivated L. brevis YM1301 reduced FINS in the T2DM mice. ^## NC vs. model; model vs. treatment groups; model vs. treatment groups (n = 10). (h) Inactivated L. brevis YM1301 reduced HOMA-IR in the T2DM mice. ^### NC vs. model; model vs. treatment groups (n = 10).

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