Nuciferine Promotes Longevity and Fitness in Caenorhabditis elegans through the Regulation of the Insulin/IGF-1 Signaling Pathway

Figure 2

Nuciferine promoted the healthspan in N2 worms. Effects of nuciferine on (a) body bending rates, (b) pharyngeal pumping rates, (c) fluorescent images of lipofuscin in N2 worms on the 10th day of adulthood, (d) relative fluorescence intensity of lipofuscin, (e) body length, and (f) body width on days 3, 6, and 9 of adulthood in nematodes. Data were represented as mean ± SD, n = 3. Statistical significance was obtained at , , , and by ANOVA with Tukey’s multiple comparisons test. ns: not significant.

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