Research Article

Selenium-Containing Protein from Selenium-Enriched Spirulina platensis Relieves Osteoporosis by Inhibiting Inflammatory Response, Osteoblast Inactivation, and Osteoclastogenesis

Figure 5

Se-SP inhibited osteoblast inactivation in ovariectomized mice. (a) Representative fluorescence images of the expression of BMP2, RUNX, Col-I, and OCN in the femur tissues. Quantification analysis of the expression of BMP2 (b), RUNX (c), Col-I (d), and OCN (e). Ovariectomy mice were treated with Se-SP and SP for 14 days, then mice were euthanized and the femurs were subjected to the analysis of osteoblast activation by staining with specific antibodies. Characters A, B, C, and D are represented as statistically different between the groups.
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