MAPK and PI3K/Akt Signalling Pathways Potentially Modulate the Enhancing Effect of Black Tea Extracts on Endo180 Expression and Collagen Internalisation

Figure 1

Effect of black tea extract (BTE) on cell viability and toxicity of BTE in human dermal fibroblasts (HDFs). (a) BTE reduced the viability of HDFs. HDFs were treated with the indicated concentrations of BTE for 1 day. Cell viability was measured as described in the “CCK-8 Assay” section. Cell viability in each treatment group is calculated as a percentage compared with the value of the untreated control group and is expressed as mean ± standard deviation of three independent experiments. Different letters denote significant differences. (b) BTE did not exert toxicity on HDFs. HDFs were treated with the indicated concentrations of BTE for 1 day. Cytotoxicity was measured and calculated as described in the “LDH Assay” section. The results are expressed as mean ± standard deviation of three independent experiments. Different letters denote significant differences at .

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