Immune-Enhancing Activity of Vitis coignetiae Extract via Increasing Cytokine and Natural Killer Cell Activity in Splenocytes and Cyclophosphamide-Induced Immunosuppressed Rats

Figure 1

Cell viability and anti-inflammatory effects of Vitis coignetiae extract (VCE) on Wistar rat splenocytes. Splenocytes were treated for 24 h with (a) VCE (0–1,000 μg/mL) and with (b) VCE (0–300 μg/mL) and cyclophosphamide (Cy) (0.8 mg/mL). Nitric oxide (NO) concentration was determined using the Griess reagent. Splenocytes were pretreated with (c) VCE (0–300 μg/mL) and (d) Cy (0.8 mg/mL) for 24 h. Levels were detected using an enzyme-linked immunosorbent assay (ELISA). Bars labeled with different superscripts have significantly different values ().

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