Liquid-State Fermented Ganoderma lucidum GANO99 Regulates Gut Microbiota and Concomitantly Modulates the Behavioral Deficits and Neurohistopathological Hallmarks of Alzheimer’s Disease in a Preclinical Transgenic Mouse Model of Alzheimer’s Disease

Figure 6

The microbial diversity of AD mice administered with the liquid-state fermented products of G. lucidum GANO99. (a) Venn diagram. The overlapping part indicates the number of OTUs. (b) The ratio of Firmicutes/Bacteroidetes of fecal microbes. (c) Alpha-diversity of gut microbiota by Chao1, ACE, Shannon, and Simpson statistical analysis. (d) Beta-diversity of gut microbiota by PLS-DA and PCA statistical analysis.

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