Physicochemical Evaluation of Diploknema butyracea Seed Extract and Formulation of Ketoconazole Ointment by Using the Fat as a Base

Table 10

Percentage of drug release for the formulations F-A, F-B, and F-C in acetic acid buffer at different time intervals.

Formulations	Active ingredient release percentage (%)
	0.5 hours	1 hour	2 hours	3 hours	4 hours	5 hours
F-A	15.93 ± 0.77^a	27.32 ± 0.66^a	42.03 ± 2.01^a	66.35 ± 0.98^a	75.15 ± 0.87^a	87.71 ± 1.44^a
F-B	17.17 ± 0.86^a	30.40 ± 0.61^b	45.3 ± 1.08^b	67.3 ± 1.18^a	77.8 ± 0.41^ab	88.89 ± 0.67^a
F-C	18.3 ± 0.23^a	31.12 ± 091^c	44.07 ± 0.68^ab	70.19 ± 0.45^b	79.18 ± 0.8^b	91.09 ± 0.19^b

Note. Different superscript letters within the same column indicate significant differences () among the formulations.