Cytotoxicity and Genotoxicity Evaluation of Some Stored Grain Insects and Their Infested Flour Using the BHK-21 Cell Line in an In Vitro Experimental Model

Table 2

Baby hamster kidney cell line (BHK-21) viability (%) at different concentrations of stored grain insects and infested flour as well as determination of IC₅₀ %.

Conc. (μg/ml)	Control flour	Grinded insects				Flour
		T. granarium	S. oryzae	R. dominica	T. castaneum	T. granarium	S. oryzae	R. dominica	T. castaneum
0	100.00	100.00	100.00	100.00	100.00	100.00	100.00	100.00	100.00
6.5	99.71 ± 3.75	95.69 ± 1.23	95.64 ± 3.84	95.93 ± 2.25	96.51 ± 3.11	99.13 ± 0.86	96.26 ± 3.75	94.48 ± 1.08	95.69 ± 5.1
12.5	99.13 ± 4.28	91.38 ± 3.15	85.47 ± 4.32	95.35 ± 3.62	83.14 ± 4.55	96.51 ± 2.11	92.82 ± 2.39	89.83 ± 4.26	91.38 ± 1.96
25	98.26 ± 3.52	54.31 ± 4.21	71.80 ± 5.37	93.90 ± 2.22	65.41 ± 3.48	93.02 ± 3.88	88.79 ± 0.99	87.21 ± 0.87	54.31 ± 2.78
50	92.44 ± 2.56	44.54 ± 2.05	52.62 ± 3.33	87.50 ± 3.48	58.72 ± 4.01	81.98 ± 2.65	83.05 ± 3.85	76.16 ± 2.44	44.54 ± 3.46
100	89.83 ± 4.21	31.69 ± 1.86	44.48 ± 2.69	77.03 ± 0.84	32.56 ± 3.21	47.67 ± 3.48	74.14 ± 4.61	56.98 ± 4.10	37.93 ± 1.32
IC 50%	808.2	36.42	67.72	376.1	56.04	96.78	410.3	138.5	46.73

Significant difference at compared with the control; values represent the ratio of the mean of four replicates ± SE (standard error).