Research Article

Nobiletin Protects Endothelial Cell Function via Upregulation of eNOS/ET-1 and Antioxidant Status-Related Genes under Nonstimulated and Inflammatory Conditions

Figure 1

Effect of increasing concentrations of citrus flavonoids: (a) nobiletin (NOB) and (b) tangeretin (TAN), hesperetin (HES), and naringenin (NAR) on NOS3 mRNA levels. Cells were incubated for 18 h with concentrations up to 25 μM. Data are presented as mean ± SD. indicates significant differences between the treatment group and untreated control group at .
(a)
(b)