[Retracted] The Association between Long Noncoding RNA over Expression and Poor Prognosis of Liver Cancer: A Meta-Analysis

Table 3

Results of meta-analysis on the correlation between LncRNA expression level and clinical features of liver cancer.

Clinical Characteristics	Number of studies included (papers)	Tests for heterogeneity		Effect of the model	Results of meta-analysis
		I^2 (%)	P value		OR (95%CI)	value
Age	39 [5, 10, 16–52]	66.5%	<0.001	Random	1.07 (0.96, 1.19)	0.253
Gender	42 [5, 10, 16–55]	0.0%	0.66	Fixed	1.03 (0.92,1.15)	0.648
Tumor size	33 [10, 16, 29, 31, 34, 36, 39, 41–52]	71.8%	<0.001	Random	2.28 (2.00,2.60)	<0.001
HBV infection	25 [10, 16, 19, 20, 24, 25, 27, 29, 31, 34, 36, 39, 41, 43, 44, 46, 52, 55]	0.0%	0.712	Fixed	1.12 (0.95,1.31)	0.182
Liver cirrhosis	18 [16, 20, 22, 25, 34, 38, 42, 44, 47, 49, 51, 55]	0.0%	0.799	Fixed	1.39 (1.16,1.66)	<0.001
Metastasis	16 [22, 23, 27, 28, 30, 34, 37, 38, 40, 41, 48, 51, 52]	72.5%	<0.001	Random	1.80 (1.49,2.18)	<0.001
H- grade	28 [5, 10, 16, 25, 28, 30, 32, 33, 35, 37, 39, 41, 42, 45, 48, 53, 54]	67.5%	<0.001	Random	0.54 (0.48,0.62)	<0.001
AFP (400)	18 [10, 16, 22, 24, 26, 35, 36, 41, 45, 47, 51, 52, 55]	41.5%	0.034	Fixed	1.46 (1.22,1.75)	<0.001
AFP (20)	9 [27, 29, 40, 42, 43, 46, 48, 50]	76.9%	<0.001	Random	1.79 (1.40,2.29)	<0.001
TNM stage	33 [5, 10, 15, 20, 22, 24, 34, 36, 43, 46, 48, 50, 51, 54]	78.9%	<0.001	Random	0.46 (0.41,0.51)	<0.001
Tumor number	25 [10, 16, 24, 26, 29, 31, 34, 35, 37, 42, 43, 46, 48, 50, 51, 55]	53.4%	0.001	Random	0.72 (0.62,0.84)	<0.001
V-invasion	22 [16, 19, 24, 26, 30, 32, 35, 37, 41, 42, 44, 45, 47, 49, 51, 55]	84.7%	<0.001	Random	2.02 (1.74,2.35)	<0.001

AFP (400): the cutoff of AFP is 400 μg/L; AFP (20): the cutoff of AFP is 20 μg/L; H-grade: histological grade; V-invasion: vascular invasion.