Research Article
A PLA2R-IgG4 Antibody-Based Predictive Model for Assessing Risk Stratification of Idiopathic Membranous Nephropathy
Table 1
The information of data set.
| No. | Feature (variable) | Value | r |
| 1 | Age (years) | 55.110 ± 15.110 | 0.175 | 2 | Gender (males/females) | 56/39 | 0.105 | 3 | Renal tubular atrophy score | 1.057 ± 0.721 | 0.080 | 4 | Renal interstitial fibrosis score | 1.100 ± 0.731 | 0.113 | 5 | Renal interstitial lymphoplasmacytic infiltrate score | 1.068 ± 0.861 | 0.187 | 6 | Total score of renal tubular and interstitium | 3.236 ± 2.138 | 0.136 | 7 | Pathological stage of IMN | 1.452 ± 0.495 | 0.009 | 8 | IF IgA | 0.220 ± 0.477 | 0.089 | 9 | IF IgM | 0.252 ± 0.635 | 0.034 | 10 | IF IgG | 2.789 ± 0.697 | 0.009 | 11 | IF C1q | 0.242 ± 0.488 | 0.098 | 12 | IF C3 | 1.205 ± 0.738 | −0.035 | 13 | Renal tissue PLA2R antigen | 0.952 ± 0.357 | −0.031 | 14 | SBP (mmHg) | 133.389 ± 14.973 | 0.017 | 15 | DBP (mmHg) | 79.989 ± 9.079 | −0.109 | 16 | Serum C3 (mg/L) | 894.305 ± 253.312 | −0.008 | 17 | Serum C4 (mg/L) | 241.147 ± 87.192 | 0.058 | 18 | Serum IgA (g/L) | 5.206 ± 28.002 | 0.061 | 19 | Serum IgG (g/L) | 7.084 ± 2.891 | −0.077 | 20 | Serum IgM (g/L) | 1.257 ± 0.637 | −0.013 | 21 | Serum albumin (g/L) | 23.335 ± 8.233 | −0.449 | 22 | Hematuria (/uL) | 102.377 ± 138.301 | −0.014 | 23 | Serum creatinine (umol/L) | 83.664 ± 34.042 | 0.168 | 24 | eGFR-EPI (ml/min) | 86.535 ± 24.060 | −0.189 | 25 | BUN (mmol/L) | 4.986 ± 1.929 | 0.172 | 26 | Serum glucose (mmol/L) | 5.142 ± 0.810 | 0.321 | 27 | Serum lithic acid (umol/L) | 344.676 ± 89.678 | 0.048 | 28 | TG (mmol/L) | 2.406 ± 1.471 | 0.415 | 29 | TC (mmol/L) | 7.119 ± 2.289 | 0.141 | 30 | LDL-C (mmol/L) | 3.902 ± 1.379 | 0.077 | 31 | HDL-C (mmol/L) | 1.323 ± 0.432 | −0.110 | 32 | WBC (×109/L) | 8.577 ± 13.978 | 0.088 | 33 | Hemoglobin (g/L) | 122.204 ± 24.962 | 0.058 | 34 | PLT (×109/L) | 219 ± 65.409 | −0.104 | 35 | C-reactive protein (mg/L) | 2.807 ± 3.167 | 0.057 | 36 | ESR (mm/H) | 53.589 ± 34.176 | 0.233 | 37 | Serum PLA2R-IgG (ng/mL) | 5243.957 ± 9282.902 | 0.394 | 38 | Serum PLA2R-IgG4 (ng/mL) | 1762.615 ± 2662.328 | 0.524 |
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denotes that each feature correlated with risk stratification of progression in IMN using Pearson correlation coefficient ( r). |