Research Article

A PLA2R-IgG4 Antibody-Based Predictive Model for Assessing Risk Stratification of Idiopathic Membranous Nephropathy

Table 1

The information of data set.

No.Feature (variable)Valuer

1Age (years)55.110 ± 15.1100.175
2Gender (males/females)56/390.105
3Renal tubular atrophy score1.057 ± 0.7210.080
4Renal interstitial fibrosis score1.100 ± 0.7310.113
5Renal interstitial lymphoplasmacytic infiltrate score1.068 ± 0.8610.187
6Total score of renal tubular and interstitium3.236 ± 2.1380.136
7Pathological stage of IMN1.452 ± 0.4950.009
8IF IgA0.220 ± 0.4770.089
9IF IgM0.252 ± 0.6350.034
10IF IgG2.789 ± 0.6970.009
11IF C1q0.242 ± 0.4880.098
12IF C31.205 ± 0.738−0.035
13Renal tissue PLA2R antigen0.952 ± 0.357−0.031
14SBP (mmHg)133.389 ± 14.9730.017
15DBP (mmHg)79.989 ± 9.079−0.109
16Serum C3 (mg/L)894.305 ± 253.312−0.008
17Serum C4 (mg/L)241.147 ± 87.1920.058
18Serum IgA (g/L)5.206 ± 28.0020.061
19Serum IgG (g/L)7.084 ± 2.891−0.077
20Serum IgM (g/L)1.257 ± 0.637−0.013
21Serum albumin (g/L)23.335 ± 8.233−0.449
22Hematuria (/uL)102.377 ± 138.301−0.014
23Serum creatinine (umol/L)83.664 ± 34.0420.168
24eGFR-EPI (ml/min)86.535 ± 24.060−0.189
25BUN (mmol/L)4.986 ± 1.9290.172
26Serum glucose (mmol/L)5.142 ± 0.8100.321
27Serum lithic acid (umol/L)344.676 ± 89.6780.048
28TG (mmol/L)2.406 ± 1.4710.415
29TC (mmol/L)7.119 ± 2.2890.141
30LDL-C (mmol/L)3.902 ± 1.3790.077
31HDL-C (mmol/L)1.323 ± 0.432−0.110
32WBC (×109/L)8.577 ± 13.9780.088
33Hemoglobin (g/L)122.204 ± 24.9620.058
34PLT (×109/L)219 ± 65.409−0.104
35C-reactive protein (mg/L)2.807 ± 3.1670.057
36ESR (mm/H)53.589 ± 34.1760.233
37Serum PLA2R-IgG (ng/mL)5243.957 ± 9282.9020.394
38Serum PLA2R-IgG4 (ng/mL)1762.615 ± 2662.3280.524

denotes that each feature correlated with risk stratification of progression in IMN using Pearson correlation coefficient (r).