[Retracted] Circular RNA mmu_circ_0001598 Contributes to IL-1β-Induced Osteoarthritis Progression by Regulating miR-127-3p

Figure 2

Effects of circ_0001598 on proliferation and apoptosis in IL-1β-induced chondrocytes. (a) Expression analyses of circ_0001598 knockdown efficiency by three different si-circRNAs in chondrocytes. (b) The effect of circ_0001598 on cell proliferation in vitro was determined by the CCK-8 assay. (c, f) Effects of circ_0001598 inhibition on COL2A1 and MMP-13 mRNA levels were determined by qRT-PCR. (d, e) The effect of circ_0001598 on cell apoptosis was measured by TUNEL. (g–i) Effects of circ_0001598 inhibition on COL2A1 and MMP-13 protein levels were determined by western blot and statistical analysis of western blots.

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