[Retracted] Circular RNA mmu_circ_0001598 Contributes to IL-1β-Induced Osteoarthritis Progression by Regulating miR-127-3p

Figure 4

Circ_0001598 exerts chondrocyte biological functions by miR-127-3p. (a) Binding sites between circ_0001598 and miR-127-3p. (b) qRT-PCR analysis of miR127-3p expression in primary chondrocytes stimulated with 0, 5, 10, 50, or 100 ng/mL for 24 h. (c) The effect of circ_0001598 on cell proliferation in vitro was determined by the CCK-8 assay. (d, e) Cell apoptosis was measured by TUNEL. (f, g) qRT-PCR analysis of MMP-13 and COL2A1 expressions in different groups. (h, i) Western blot analysis of COL2A1 and MMP-13 expressions in different groups and statistical analysis of western blots.

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