Research Article
[Retracted] Prescription of Sageretia hamosa Brongn Relieved Goiter through Promoted Apoptosis of Thyroid Cells via miR-511-3p and PTEN/PI3K/Akt Pathway
Figure 5
SHB prescription effected proliferation and apoptosis of thyroid cells through regulated miR-511-3p/PTEN/PI3K/Akt pathway. (a) Protein expression of PTEN measured by western blotting. (b) Cell cycle distribution of FRTL-5 and Htori-3 measured by flow cytometry. (c) Cell viability rate of FRTL-5 and Htori-3 measured by CCK-8. (d) Cell apoptosis rate of FRTL-5 and Htori-3 measured by flow cytometry. (e) Expression of apoptosis-related proteins Bcl-2, Bax, and caspase-3 measured by western blotting. < 0.05 vs. normal group; < 0.01 vs. normal group; < 0.001 vs. normal group; # < 0.05 vs. blank group; ## < 0.01 vs. blank group; ### < 0.001 vs. blank group; Δ < 0.05 vs. 740 Y–P group; ΔΔ < 0.01 vs. 740 Y–P group; ΔΔΔ < 0.001 vs. 740 Y–P group.
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