miR-130-3p Promotes MTX-Induced Immune Killing of Hepatocellular Carcinoma Cells by Targeting EPHB4

Figure 1

miR-130-3p suppresses migration and proliferation of HCC cells. (a) CR evaluation of miR-130a-3p expression in HCC tumor tissues and regular tissues adjoining to cancer. (b) EdU binding assay after transfection of HCC cells with NC and mimic. (c) Transwell assay after transfection of HCC cells with NC and mimic. (d) Wound healing test of HCC cells after transfection of HCC cells with NC and mimic. (e) CCK8 assay after therapy of HCC cells with MTX for 24 hours. (f) AnnexinV analysis of apoptosis rate. (g) Western blot evaluation of molecules linked to the apoptotic pathway.

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