[Retracted] Passive Prescription of Secondary Prevention Medical Therapy during Index Hospitalization for Acute Myocardial Infarction Is Prevalent and Associated with Adverse Clinical Outcomes

Table 2

Predictors of adherence to discharged and six-month medical therapy.

	Adjusted OR	95% CI	value
Aspirin on discharge
Age (per year)	0.94	0.91–0.97	0.001
Index revascularization	2.77	1.13–6.82	0.026
Aspirin before admission	4.84	1.90–12.30	0.001
Clopidogrel on discharge
eGFR (mL/min/1.73 m^2)	1.01	1.00–1.02	0.037
Hemoglobin (g/dL)	1.17	1.05–1.29	0.004
Killip class (III-IV)	0.45	0.23–0.86	0.016
Index revascularization	34.28	22.94–51.22	<0.001
Beta-blockers on discharge
Age (per year)	0.97	0.96–0.99	<0.001
NSTEMI	1.54	1.18–2.02	0.002
History of hypertension	1.75	1.31–2.32	<0.001
Heart failure on admission	0.58	0.35–0.95	0.032
Beta-blockers before admission	2.50	1.83–3.42	<0.001
ACEI/ARBs on discharge
Systolic blood pressure (per mmHg)	1.01	1.00–1.02	<0.001
Diabetes mellitus	1.43	1.03–1.98	0.033
ACEI/ARBs before admission	2.93	1.97–4.34	<0.001
Statins on discharge
Age (per year)	0.95	0.94–0.97	<0.001
STEMI	1.94	1.32–2.87	0.001
Albumin (per g/l)	1.08	1.04–1.12	<0.001
Peak creatinine (per μmol/l)	0.99	0.98–1.01	0.018
Statins before admission	8.27	0.35–15.71	<0.001
Combined medication use on discharge
Diastolic blood pressure (per mmHg)	1.01	1.00–1.03	0.005
Index revascularization	9.6	5.60–16.5	<0.001
ACEI/ARBs before admission	1.92	1.26–2.92	0.003
Aspirin at 6-month
Index revascularization	1.97	1.08–3.58	0.027
Aspirin on discharge	15.13	7.13–32.13	<0.001
Clopidogrel at 6-month
Albumin during hospitalization (g/L)	1.05	1.01–1.09	0.018
History of revascularization	2.04	1.15–3.63	0.015
Index revascularization	2.51	1.45–4.35	0.001
Clopidogrel on discharge	6.02	3.42–10.60	<0.001
Beta-blockers at 6-month
Current smoker	0.54	0.34–0.85	0.008
Heart rate during hospitalization (bpm)	1.01	1.00–1.02	0.029
Albumin during hospitalization (g/L)	1.04	1.01–1.08	0.047
Beta-blockers on discharge	19.70	13.00–29.85	<0.001
ACEI/ARBs at 6-month
Hypertension	1.51	1.01–2.26	0.044
CHF	2.27	1.32–3.91	0.003
AF	0.274	0.09–0.87	0.029
Presented with STEMI	1.92	1.28–2.89	0.002
ACEI/ARBs on discharge	15.43	10.36–22.98	<0.001
Statins at 6-month
Statins on discharge	26.30	15.90–43.51	<0.001
Combined medication use at 6-month
History of revascularization	1.97	1.09–3.53	0.024
Index revascularization	2.80	1.59–4.93	<0.001
Statins on discharge	8.24	5.35–12.70	<0.001

All the data used in analyzing were adjusted with excluding the patients who have contraindications. ⁺Analysis was performed using multivariable logistic regression, and variables in the model include baseline characteristics, medical histories, medication before admission, presentation of AMI, laboratory results during hospitalization, and procedures during index admission. ACEI/ARBs, angiotensin-converting enzyme inhibitor (ACEI), or angiotensin II receptor blockers (ARB); CI, confidence interval; OR, odds ratio; STEMI, ST-elevated myocardial infarction; NSTEMI, non-ST-elevated myocardial infarction; eGFR, estimated glomerular filtration rate; CHF: congestive heart failure; AF: atrial fibrillation; Combined medication: combined using five medications including aspirin, clopidogrel, beta-blockers, ACEI/ARBs, and statins