Phenotypic Screening of Molecular Docking Enriched Chemical Libraries from Targets Identified in Ischemic Stroke Genome Data by Network-Based Method

<div>Filtering compounds from SPECS library to targets implicated in ischemic stroke by docking to pockets identified by SiteMap of IS-specific druggable proteins. (b) Histogram showing number of compounds docked to predicted IS-specific targets. (c–e) Histogram plots portraying the rate of compounds that are predicted to bind the IS-specific targets of 2ZVN, 3BRT, and 3BRV, respectively. (f) Pangram of filtered 605 compounds to IS-specific targets.</div>

Journal of Healthcare Engineering

fig2

Figure 2

Figure 2: Phenotypic Screening of Molecular Docking Enriched Chemical Libraries from Targets Identified in Ischemic Stroke Genome Data by Network-Based Method 

Figure 2 | Phenotypic Screening of Molecular Docking Enriched Chemical Libraries from Targets Identified in Ischemic Stroke Genome Data by Network-Based Method 