Association of Platelet-to-Lymphocyte Ratio with Stroke-Associated Pneumonia in Acute Ischemic Stroke
Table 1
Comparison of the characteristics of AIS patients according to the onset of SAP.
Characteristics
Total (N = 295)
Non-SAP (N = 255)
SAP (N = 40)
P value
Age, years, mean ± SD
69.5 ± 12.0
68.1 ± 11.7
77.5 ± 10.6
<0.001
Male, n (%)
196 (66.4)
171 (67.1)
25 (62.5)
0.570
Length of hospitalization, days, median (IQR)
14.0 (11.0, 17.0)
14.0 (11.0, 16.0)
14.5 (9.0, 33.0)
0.241
Baseline NIHSS, median (IQR)
3 (1, 7)
3 (1, 5)
14 (7, 18)
<0.001
Dysphagia, n (%)
49 (16.6)
15 (5.8)
34 (85.0)
<0.001
Current smoking, n (%)
96 (32.5)
85 (33.3)
11 (27.5)
0.464
Coronary artery disease, n (%)
88 (29.8)
72 (28.2)
16 (40.0)
0.131
Hypertension, n (%)
229 (77.6)
196 (76.9)
33 (82.5)
0.426
Diabetes, n (%)
106 (35.9)
96 (37.6)
10 (25.0)
0.121
Previous stroke, n (%)
81 (27.5)
66 (25.9)
15 (37.5)
0.126
Atrial fibrillation, n (%)
46 (15.6)
29 (11.4)
17 (42.5)
<0.001
OCSP
TACI, n (%)
15 (5.1)
5 (2.0)
10 (25.0)
<0.001
PACI, n (%)
90 (30.5)
78 (30.6)
12 (30.0)
0.940
POCI, n (%)
39 (13.2)
30 (11.8)
9 (22.5)
0.062
LACI, n (%)
151 (51.2)
142 (55.7)
9 (22.5)
<0.001
TC, mmol/L, median (IQR)
4.2 (3.5, 5.0)
4.3 (3.6, 5.0)
4.0 (3.1, 4.9)
0.086
TG, mmol/L, median (IQR)
1.2 (0.9, 1.7)
1.3 (1.0, 1.8)
0.9 (0.7, 1.3)
<0.001
LDL-C, mmol/L, median (IQR)
2.4 (1.8, 3.0)
2.4 (1.8, 3.0)
2.2 (1.8, 2.8)
0.306
Neutrophils, ×109/L, median (IQR)
4.3 (3.3, 6.0)
4.0 (3.1, 5.3)
7.3 (6.0, 9.6)
<0.001
Lymphocytes, ×109/L, median (IQR)
1.6 (1.3, 2.1)
1.8 (1.4, 2.1)
1.1 (0.9, 1.6)
<0.001
PLT, ×109/L, median (IQR)
216.0 (179.0, 253.0)
216.0 (180.0, 253.0)
210.5 (152.3, 247.8)
0.137
PLR, median (IQR)
126.7 (99.6, 175.3)
123.2 (98.0, 163.8)
161.2 (114.1, 209.2)
0.001
NIHSS, National Institute of Health Stroke Scale; OCSP, Oxfordshire Community Stroke Project; TACI, total anterior circulation infarct; PACI, partial anterior circulation infarct; POCI, posterior circulation infarct; LACI, lacunar circulation infarct; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; PLT, platelet; PLR, platelet-to-lymphocyte ratio; SD, standard deviation; IQR, interquartile range; SAP, stroke-associated pneumonia. P values less than 0.05 were considered statistically significant.