Research Article

Association of Platelet-to-Lymphocyte Ratio with Stroke-Associated Pneumonia in Acute Ischemic Stroke

Table 1

Comparison of the characteristics of AIS patients according to the onset of SAP.

CharacteristicsTotal (N = 295)Non-SAP (N = 255)SAP (N = 40)P value

Age, years, mean ± SD69.5 ± 12.068.1 ± 11.777.5 ± 10.6<0.001
Male, n (%)196 (66.4)171 (67.1)25 (62.5)0.570
Length of hospitalization, days, median (IQR)14.0 (11.0, 17.0)14.0 (11.0, 16.0)14.5 (9.0, 33.0)0.241
Baseline NIHSS, median (IQR)3 (1, 7)3 (1, 5)14 (7, 18)<0.001
Dysphagia, n (%)49 (16.6)15 (5.8)34 (85.0)<0.001
Current smoking, n (%)96 (32.5)85 (33.3)11 (27.5)0.464
Coronary artery disease, n (%)88 (29.8)72 (28.2)16 (40.0)0.131
Hypertension, n (%)229 (77.6)196 (76.9)33 (82.5)0.426
Diabetes, n (%)106 (35.9)96 (37.6)10 (25.0)0.121
Previous stroke, n (%)81 (27.5)66 (25.9)15 (37.5)0.126
Atrial fibrillation, n (%)46 (15.6)29 (11.4)17 (42.5)<0.001
OCSP
 TACI, n (%)15 (5.1)5 (2.0)10 (25.0)<0.001
 PACI, n (%)90 (30.5)78 (30.6)12 (30.0)0.940
 POCI, n (%)39 (13.2)30 (11.8)9 (22.5)0.062
 LACI, n (%)151 (51.2)142 (55.7)9 (22.5)<0.001
 TC, mmol/L, median (IQR)4.2 (3.5, 5.0)4.3 (3.6, 5.0)4.0 (3.1, 4.9)0.086
 TG, mmol/L, median (IQR)1.2 (0.9, 1.7)1.3 (1.0, 1.8)0.9 (0.7, 1.3)<0.001
 LDL-C, mmol/L, median (IQR)2.4 (1.8, 3.0)2.4 (1.8, 3.0)2.2 (1.8, 2.8)0.306
 Neutrophils, ×109/L, median (IQR)4.3 (3.3, 6.0)4.0 (3.1, 5.3)7.3 (6.0, 9.6)<0.001
 Lymphocytes, ×109/L, median (IQR)1.6 (1.3, 2.1)1.8 (1.4, 2.1)1.1 (0.9, 1.6)<0.001
 PLT, ×109/L, median (IQR)216.0 (179.0, 253.0)216.0 (180.0, 253.0)210.5 (152.3, 247.8)0.137
 PLR, median (IQR)126.7 (99.6, 175.3)123.2 (98.0, 163.8)161.2 (114.1, 209.2)0.001

NIHSS, National Institute of Health Stroke Scale; OCSP, Oxfordshire Community Stroke Project; TACI, total anterior circulation infarct; PACI, partial anterior circulation infarct; POCI, posterior circulation infarct; LACI, lacunar circulation infarct; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; PLT, platelet; PLR, platelet-to-lymphocyte ratio; SD, standard deviation; IQR, interquartile range; SAP, stroke-associated pneumonia. P values less than 0.05 were considered statistically significant.