PARP-1 Inhibition Repressed Imbalance of Th17 and Treg Cells in Preterm Rats with Intrauterine Infection-Induced Acute Respiratory Distress Syndrome by Reducing the Expression Level of IL-6

Figure 4

Increased IL-6 promotes Th17/Treg imbalance in PARP-1 inhibitor and E.coli cotreated CD4⁺ T cells from lung tissues of rats. Flow cytometric analysis was performed to assess the proportion of Th17 cells and Treg cells in CD4⁺ cells from the lung tissues of rats in the E.coli + PARP-1 inhibitor group. , , Vs. E.coli + PARP-1 inhibitor. Each experiment was repeated three times.