Journal of Healthcare Engineering

Research Article

Study on the Clinical Implications of NLR and PLR for Diagnosing Frailty in Maintenance Hemodialysis Patients and Their Correlations with Patient Prognosis

Table 1

Comparison of related influencing factors of frailty in patients with 1MHD.


Categories	Frailty group (n = 72)	Nonfrailty group (n = 113)	χ²/t/Z value

Male (n (%))	31 (43.06)	57 (50.44)	0.962	0.327
Age (years)	59.4 ± 13.7	53.2 ± 13.9	3.261	0.001
Dialysis duration (months)	66.94 (35.12, 88.72)	67.22 (34.21, 86.23)	0.573	0.632
Education years	8.65 ± 2.67	8.94 ± 2.86	0.582	0.552
Dialysis adequacy	1.43 ± 0.26	1.66 ± 0.27	5.726	<0.001
Type 2 diabetes mellitus (n (%))	28 (38.89)	31 (27.43)	2.657	0.103
Coronary artery disease (n (%))	14 (19.44)	19 (16.81)	0.208	0.649
SA (g/L)	37.16 ± 4.01	40.41 ± 3.25	6.058	<0.001
Hemoglobin (g/L)	107.62 ± 19.81	112.14 ± 15.47	1.734	0.085
Predialysis blood urea nitrogen (mmol/L)	25.74 ± 7.25	26.78 ± 7.36	0.943	0.347
Predialysis serum creatinine (umol/L)	583.82 (252.34, 762.12)	629.72 (272.67, 782.45)	1.432	0.156
Uric acid (umol/L)	463.24 ± 74.59	446.87 ± 71.26	1.496	0.136
Triglyceride (mmol/L)	1.71 (1.17, 2.34)	1.84 (1.12, 2.19)	0.675	0.485
Total cholesterol (mmol/L)	3.84 ± 0.79	3.92 ± 0.73	0.451	0.704
High-density lipoprotein (mmol/L)	1.01 ± 0.33	1.09 ± 0.36	1.522	0.130
Low-density lipoprotein (mmol/L)	3.38 ± 0.74	3.42 ± 0.71	0.368	0.714
Blood potassium (mmol/L)	4.74 ± 0.78	4.52 ± 0.74	1.930	0.055
Blood calcium (mmol/L)	2.04 ± 0.21	2.07 ± 0.23	0.894	0.372
Blood phosphorus (mmol/L)	1.92 ± 0.48	1.85 ± 0.49	0.955	0.341
NLR	4.18 ± 1.02	2.55 ± 0.95	11.091	<0.001
PLR	129.96 ± 12.62	112.62 ± 13.36	8.787	<0.001
Body mass index (kg/m²)	20.26 ± 2.58	21.01 ± 2.76	1.823	0.07
GS (kg)	20.11(14.32, 21.21)	28.72 (19.21, 36.72)	4.785	<0.001
WS (m/s)	0.65 ± 0.26	0.76 ± 0.25	2.921	0.004
Bicep’s circumference (mm)	28.62 ± 2.31	29.11 ± 3.24	1.115	0.126
MAMC (mm)	21.62 ± 2.74	23.08 ± 2.72	3.548	<0.001

SA, serum albumin; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; GS, grip strength; WS, walking speed; MAMC, midarm muscle circumference.