Research Article

Construction of a Diagnostic Model for Lymph Node Metastasis of the Papillary Thyroid Carcinoma Using Preoperative Ultrasound Features and Imaging Omics

Table 3

The predictive performance of these models in the training and testing sets.

ModelsCut-offSensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)AUC (95% CI)Accuracy (95% CI)

Model 1a0.3480.849 (0.806–0.891)0.851 (0.817–0.886)0.790 (0.744–0.837)0.895 (0.864–0.925)0.913 (0.893–0.934)0.850 (0.823–0.877)
Model 1b0.3480.738 (0.661–0.815)0.771 (0.707–0.835)0.710 (0.632–0.788)0.795 (0.733–0.857)0.813 (0.762–0.863)0.757 (0.708–0.806)
Model 2a0.4370.808 (0.761–0.855)0.868 (0.836–0.901)0.802 (0.755–0.849)0.873 (0.840–0.905)0.913 (0.892–0.934)0.844 (0.817–0.872)
Model 2b0.4370.730 (0.653–0.808)0.789 (0.727–0.851)0.724 (0.647–0.802)0.794 (0.732–0.856)0.818 (0.769–0.868)0.764 (0.715–0.812)
Model 3a0.3600.886 (0.848–0.924)0.827 (0.790–0.863)0.772 (0.725–0.818)0.916 (0.888–0.944)0.941 (0.925–0.957)0.850 (0.823–0.877)
Model 3b0.3600.762 (0.688–0.836)0.723 (0.655–0.791)0.676 (0.599–0.753)0.800 (0.736–0.864)0.821 (0.772–0.871)0.740 (0.689–0.790)
Model 4a0.5000.823 (0.777–0.868)0.966 (0.948–0.983)0.941 (0.911–0.971)0.892 (0.863–0.921)0.984 (0.977–0.990)0.909 (0.887–0.931)
Model 4b0.5000.667 (0.584–0.749)0.910 (0.866–0.953)0.848 (0.778–0.919)0.782 (0.724–0.841)0.857 (0.811–0.902)0.805 (0.759–0.850)

aUsing the training set; busing the testing set. PPV: positive predictive value; NPV: predictive value; AUC: area under the curve; CI: confidence internal.