Research Article
Psoriasis Vulgaris of Blood Heat Syndrome in Plasma Based on Widely Targeted Techniques
Table 2
Significantly different metabolites of BH-PPG and NBH-PPG from the normal control group.
| | Index | Differential metabolites | Metabolite categories | BH-PPG v NPG | NBH-PPG v NPG | Type | | VIP value | Log2FC | VIP value | Log2FC |
| | MEDN636 | Ginkgolic acid | Organic acids and the derivatives | 2.01 | 19.59 | 1.96 | 19.54 | Up | | MEDN196 | Pyrroloquinoline quinone | Organic acids and the derivatives | 2.01 | 16.57 | 1.96 | 16.65 | Up | | MEDN009 | L-Aspartate amino | Amino acids and the metabolites | 2.10 | 14.85 | 1.96 | 14.96 | Up | | MEDN195 | Phosphopyridoxal | Pyridine and the derivatives | 2.10 | 11.79 | 1.95 | 11.73 | Up | | MEDN499 | Argininosuccinic acid | Organic acids and the derivatives | 1.42 | 4.19 | 1.37 | 4.14 | Up | | MEDP443 | Leucovorin | Pteridine and the derivatives | 1.83 | 3.13 | 1.80 | 3.18 | Up | | MEDN506 | N-Acetylglucosamine 1-phosphate | Carbohydrate and the metabolites | 2.00 | 3.02 | 1.92 | 3.09 | Up | | MEDP831 | DL-1-Amino-2-propanol | Alcohols | 1.63 | 2.35 | 1.25 | 2.51 | Up | | MEDP016 | L-Glutamic acid | Amino acids and the metabolites | 1.79 | 1.90 | 1.61 | 1.72 | Up | | MEDP860 | Glutamate | Amino acids and the derivatives | 1.76 | 1.80 | 1.51 | 1.48 | Up | | MEDN206 | Citromalic acid | Amino acids and the metabolites | 2.10 | −19.7 | 1.96 | −19.7 | Down | | MEDN292 | 3-Hydroxybutyric acid | Organic acids and the derivatives | 2.10 | −18.98 | 1.96 | −18.98 | Down | | MEDN244 | Orotic acid | Coenzymes and vitamins | 2.10 | −18.11 | 1.96 | −18.11 | Down | | MEDN484 | Β-Hydroxypyruvic acid | Organic acids and the derivatives | 1.96 | −18.05 | 1.83 | −18.05 | Down | | MEDP718 | Methyl isobutyrate | Organic acids and the derivatives | 2.10 | −15.88 | 1.96 | −15.88 | Down | | MEDN283 | 2-Hydroxybutyric acid | Organic acids and the derivatives | 2.10 | −15.81 | 1.96 | −15.81 | Down | | MEDN726 | Capraldehyde | Aldehydes | 2.10 | −15.03 | 1.96 | −15.03 | Down | | MEDN738 | 2, 6-Dimethylnaphthalene | Benzene and the derivatives | 2.10 | −15.01 | 1.96 | −15.01 | Down | | MEDP151 | 2-Hydroxy-6-aminopurine | Nucleotide and the metabolites | 2.10 | −14.51 | 1.96 | −14.51 | Down | | MEDN469 | Citraconic acid | Organic acids and the derivatives | 2.07 | −11.55 | 1.96 | −19.11 | Down |
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Note. List of top 10 upregulated and downregulated differential metabolites.
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