Research Article

Psoriasis Vulgaris of Blood Heat Syndrome in Plasma Based on Widely Targeted Techniques

Table 2

Significantly different metabolites of BH-PPG and NBH-PPG from the normal control group.

IndexDifferential metabolitesMetabolite categoriesBH-PPG v NPGNBH-PPG v NPGType
VIP valueLog2FCVIP valueLog2FC

MEDN636Ginkgolic acidOrganic acids and the derivatives2.0119.591.9619.54Up
MEDN196Pyrroloquinoline quinoneOrganic acids and the derivatives2.0116.571.9616.65Up
MEDN009L-Aspartate aminoAmino acids and the metabolites2.1014.851.9614.96Up
MEDN195PhosphopyridoxalPyridine and the derivatives2.1011.791.9511.73Up
MEDN499Argininosuccinic acidOrganic acids and the derivatives1.424.191.374.14Up
MEDP443LeucovorinPteridine and the derivatives1.833.131.803.18Up
MEDN506N-Acetylglucosamine 1-phosphateCarbohydrate and the metabolites2.003.021.923.09Up
MEDP831DL-1-Amino-2-propanolAlcohols1.632.351.252.51Up
MEDP016L-Glutamic acidAmino acids and the metabolites1.791.901.611.72Up
MEDP860GlutamateAmino acids and the derivatives1.761.801.511.48Up
MEDN206Citromalic acidAmino acids and the metabolites2.10−19.71.96−19.7Down
MEDN2923-Hydroxybutyric acidOrganic acids and the derivatives2.10−18.981.96−18.98Down
MEDN244Orotic acidCoenzymes and vitamins2.10−18.111.96−18.11Down
MEDN484Β-Hydroxypyruvic acidOrganic acids and the derivatives1.96−18.051.83−18.05Down
MEDP718Methyl isobutyrateOrganic acids and the derivatives2.10−15.881.96−15.88Down
MEDN2832-Hydroxybutyric acidOrganic acids and the derivatives2.10−15.811.96−15.81Down
MEDN726CapraldehydeAldehydes2.10−15.031.96−15.03Down
MEDN7382, 6-DimethylnaphthaleneBenzene and the derivatives2.10−15.011.96−15.01Down
MEDP1512-Hydroxy-6-aminopurineNucleotide and the metabolites2.10−14.511.96−14.51Down
MEDN469Citraconic acidOrganic acids and the derivatives2.07−11.551.96−19.11Down

Note. List of top 10 upregulated and downregulated differential metabolites.