Research Article
Estradiol (E2) Reduction Adversely Affect the Embryo Quality and Clinical Outcomes of In Vitro Fertilization and Embryo transfer (IVF-ET)
Table 2
Comparison of the stimulation variables and clinical outcomes between group A and group B.
| | Variables | Group A (n = 120) | Group B (n = 180) | value |
| | Starting dosage of Gn (IU) | 165.02 ± 53.32 | 180.59 ± 55.32 | 0.016 | | Duration of Gn (d) | 14.95 ± 3.95 | 11.21 ± 1.98 | <0.001 | | Total dosage of Gn (IU) | 2721.19 ± 1291.25 | 2258.64 ± 876.05 | <0.001 | | Endometrial thickness on the hCG day (mm) | 11.09 ± 2.17 | 11.14 ± 1.97 | 0.850 | | LH level on the hCG day (IU/L) | 0.57 ± 0.49 | 0.75 ± 0.58 | 0.005 | | E2 level on the hCG day (pg/ml) | 1906.76 ± 1190.35 | 2203.77 ± 1032.71 | 0.027 | | P level on the hCG day (ng/mL) | 0.57 ± 0.30 | 0.59 ± 0.28 | 0.429 | | Number of oocytes retrieved (n) | 12.89 ± 5.76 | 12.09 ± 5.60 | 0.231 | | Rate of high-quality embryos (%) | 0.79 ± 0.23 | 0.84 ± 0.20 | 0.048 | | Blastocysts available rate (%) | 0.45 ± 0.30 | 0.46 ± 0.28 | 0.801 | | Clinical pregnancy rate (%) | 58.33% (70/120) | 70.56% (127/180) | 0.029 | | Early abortion rate (%) | 18.57% (13/70) | 6.30% (8/127) | 0.008 | | Ongoing pregnancy rate (%) | 47.50% (57/120) | 66.11% (119/180) | 0.001 | | Live birth rate (%) | 43.33% (52/120) | 65.56% (118/180) | <0.001 |
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hCG, human chorionic gonadotropin; Gn, gonadotropin.
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