Estradiol (E₂) Reduction Adversely Affect the Embryo Quality and Clinical Outcomes of In Vitro Fertilization and Embryo transfer (IVF-ET)

Table 3

Comparison of basic characteristics between the spontaneously falling E₂ group and the drug dosage reduction group.

Variables	Spontaneously reduction (n = 63)	Dose-adjusted reduction (n = 57)	value
Age (years)	30.67 ± 4.18	30.02 ± 4.09	0.392
BMI (kg/m^2)	23.04 ± 3.62	20.93 ± 2.92	0.001
AFC (n)	22.42 ± 10.35	21.06 ± 9.59	0.497
Protocol
Long % (n)	12.70% (8/63)	1.75% (1/57)	0.034
IPM% (n)	7.94% (5/63)	15.79% (9/57)	0.181
IPF% (n)	79.36 (50/63)	82.46% (47/57)	0.667

BMI, body mass index. Long: long protocol; IPM: improved prolonged protocol in the midluteal phase; IPF: improved prolonged protocol in the follicular phase; AFC: antral follicle counts.