| | Variable | All, n = 342 | NAT, n = 36 | AP, n = 134 | VKA, n = 30 | NOACs, n = 142 |
| | Age, years | 79.16 ± 8.72 | 81.17 ± 10.76 | 79.06 ± 8.91 | 78.63 ± 7.69 | 78.87 ± 8.17 | | Group 65–74, n (%) | 112 (32.75) | 11 (30.56) | 46 (34.33) | 9 (30.00) | 46 (32.39) | | Group 65–74, years | 68.97 ± 3.00 | 68.18 ± 3.57 | 68.72 ± 3.15 | 69.67 ± 3.04 | 69.28 ± 2.72 | | Group 75–84, n (%) | 121 (35.38) | 9 (25.00) | 44 (32.84) | 14 (46.67) | 54 (38.03) | | Group 75–84, years | 79.45 ± 2.73 | 78.33 ± 2.78 | 79.91 ± 2.81 | 79.21 ± 2.91 | 79.31 ± 2.61 | | Group ≥85, n (%) | 109 (31.87) | 16 (44.44) | 44 (32.84) | 7 (23.33) | 42 (29.58) | | Group ≥85, years | 89.32 ± 3.21 | 91.69 ± 3.30 | 89.02 ± 3.21 | 89.00 ± 2.89 | 88.79 ± 2.94 | | Male, sex, n (%) | 160 (46.78) | 8 (22.22) | 69 (51.49) | 9 (30.00) | 74 (52.11) | | Previous bleeding, n (%) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | | Previous stroke, n (%) | 56 (16.37) | 1 (2.78) | 25 (18.66) | 5 (16.67) | 25 (17.61) | | Previous TIA, n (%) | 32 (9.36) | 2 (5.56) | 14 (10.45) | 2 (6.67) | 14 (9.86) | | Heart failure, n (%) | 162 (47.37) | 9 (25.00) | 57 (42.54) | 24 (80.00) | 72 (50.70) | | Hypertension, n (%) | 304 (88.89) | 33 (91.67) | 121 (90.30) | 25 (83.33) | 125 (88.03) | | Diabetes, n (%) | 131 (38.30) | 7 (19.44) | 62 (46.27) | 12 (40.00) | 50 (35.21) | | Coronary artery disease, n (%) | 148 (43.27) | 6 (16.67) | 81 (60.45) | 8 (26.67) | 53 (37.32) | | Chronic kidney disease, n (%) | 108 (31.58) | 11 (30.56) | 45 (33.58) | 14 (46.67) | 38 (26.76) | | Peripheral arterial disease, n (%) | 18 (5.26) | 2 (5.56) | 7 (5.22) | 2 (6.67) | 7 (4.93) | | Hemoglobin (g/L) | 115.65 ± 21.48 | 108.19 ± 23.55 | 114.65 ± 20.63 | 106.57 ± 22.32 | 120.39 ± 20.46 | | NT-proBNP (pg/mL) | 4,925.88 ± 9,339.50 | 4,238.57 ± 9,798.98 | 5,698.02 ± 10,484.23 | 7,949.40 ± 11,013.76 | 3,731.99 ± 7,376.84 | | cTnT (ng/mL) | 0.12 ± 0.55 | 0.31 ± 1.50 | 0.11 ± 0.32 | 0.13 ± 0.18 | 0.07 ± 0.23 | | GDF-15 (pg/mL) | 4,610.85 ± 4,513.30 | 4,138.94 ± 4,221.84 | 5,302.78 ± 4,844.91 | 6,259.43 ± 6,490.14 | 3,729.25 ± 3,487.33 | | Group 65–74 (pg/mL) | 3,674.68 ± 4,494.31 | 1,917.00 ± 1,901.88 | 4,554.96 ± 5,072.16 | 4,882.22 ± 6,092.32 | 2,971.15 ± 3,788.10 | | Group 75–84 (pg/mL) | 4,506.32 ± 3,997.35 | 5,111.22 ± 4,640.24 | 4,838.43 ± 4,140.50 | 5,145.57 ± 4,125.49 | 3,969.17 ± 3,780.08 | | Group ≥85 (pg/mL) | 5,691.91 ± 4,867.80 | 5,119.63 ± 4,741.36 | 6,548.95 ± 5,111.54 | 10,257.86 ± 9,634.98 | 4,251.07 ± 2,569.64 | | CREA (umol/L) | 130.38 ± 126.40 | 126.67 ± 129.60 | 155.57 ± 172.78 | 160.10 ± 112.94 | 101.06 ± 43.97 | | ALT (u/l) | 30.24 ± 86.95 | 25.17 ± 55.60 | 34.70 ± 80.22 | 22.33 ± 15.68 | 28.97 ± 106.69 | | CHA2DS2-VASc score | 5 (4, 6) | 4 (3, 5) | 5 (4, 6) | 5 (4, 7) | 5 (4, 6) | | HAS-BLED score | 3 (2, 4) | 2 (2, 4) | 3 (3, 4) | 3 (2, 4) | 3 (2, 4) | | ABC-stroke score with OAC (%) | 1.53 (0.83, 3.07) | — | — | 2.76 (1.71, 3.69) | 1.43 (0.93, 2.53) | | ABC-stroke score with non-OAC (%) | 4.59 (2.49, 9.21) | 2.54 (1.48, 5.45) | 4.70 (2.24, 9.69) | — | — | | ABC-AF bleeding score (%) | 5.16 (2.71, 10.56) | 4.78 (1.93, 14.24) | 6.01 (2.69, 12.58) | 7.99 (5.16, 12.70) | 4.23 (2.68, 7.86) |
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Continuous variables are summarized as median (first quartile-third quartile). ABC indicates Age, Biomarkers, Clinical History; AF, atrial fibrillation; TIA, transient ischemic attack; NT-proBNP, N-terminal pro-B-type natriuretic peptide; cTnT, cardiac troponin T; GDF-15, growth differentiation factor; CREA, creatinine; ALT, alanine aminotransferase; NAT, no antithrombotic treatment; AP, antiplatelet; VKA, vitamin K antagonists; NOACs, non-vitamin K antagonist.
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