The Clinical Efficacy of Double Plasma Molecular Absorption System Combined with Plasma Exchange in the Treatment of Acute-on-Chronic Liver Failure: A Systematic Review and Meta-Analysis
Table 1
Basic characteristics of the included literature.
Study
Year
Sample time (year.month)
Cases treat/con
Age (years)
Sex (male/female)
Study design
Outcome measures
Treat group
Treat group
Treat group
Con group
Liu Xiaoyan
2018
2016.02∼2016.12
30/32
45 ± 12
42 ± 13
26/4
28/4
Retrospective
①④⑤⑥⑦⑨⑩
Du Zhen
2021
2016.06∼2018.12
34/38
47.5 ± 10.2
48.2 ± 8.5
28/6
29/9
Retrospective
①②③④⑤⑥⑦⑧
Li Yongchao
2020
2016.09∼2017.10
30/30
42.1 ± 2.3
42.1 ± 2.3
17/13
17/13
RCT
①②⑤⑦⑧⑨⑩
Zuo Tongkun
2020
2013.01∼2019.01
25/25
46.25 ± 12.05
43.68 ± 11.87
19/6
18/7
Retrospective
①②⑤⑥⑧⑨⑩
Li Chunyu
2021
NR
35/32
49.12 ± 6.54
49.31 ± 5.98
21/14
20/12
RCT
①③④⑤⑥⑦
Qin Hua
2019
2016.1∼2018.12
32/37
45.1 ± 10.6
42.8 ± 11.3
26/6
29/8
Retrospective
①②⑤⑥⑦⑨
Xie Nengwen
2021
2018.01∼2019.12
56/56
36.30 ± 5.41
35.89 ± 4.88
38/18
40/16
Retrospective
①②③④⑤⑥⑦⑧⑨⑩
Chen Li
2020
2013.01∼2019.06
30/23
49.3 ± 12.08
46.7 ± 10.9
20/10
20/3
Retrospective
①④⑤⑦
Jia Yao
2019
2016.06∼2018.06
54/77
47.6 ± 11.5
43.8 ± 14.2
38/16
54/23
Retrospective
①②③⑤⑦⑧
Nong Cunli
2019
2015.01∼2017.12
33/31
39.33 ± 8.16
39.26 ± 9.27
28/5
27/4
RCT
①③⑤⑥⑦
Qin Hao
2020
2017.01∼2018.12
43/43
45.63 ± 5.51
45.16 ± 5.47
24/19
25/18
RCT
① ②⑤⑥⑨
Note. Treat: treatment; Con: control; RCT: randomized controlled trial; and NR: not reported. ① effective rate, ② prothrombin activity after treatment (PTA), ③ international normalized ratio after treatment (INR), ④ prothrombin time after treatment (PT), ⑤ total bilirubin level after treatment (TBIL), ⑥ alanine aminotransferase level after treatment (ALT), ⑦ albumin level after treatment (ALB), ⑧ creatinine level after treatment (Cr), ⑨ platelet level after treatment (PLT), and ⑩ hemoglobin level after treatment (HGB).
