Development of a Gene Risk Signature for Patients of Pancreatic Cancer

Figure 3

Construction of a multigene signature. (a) Univariate Cox analysis of genes within the brown module, screening of prognosis-related genes, and forest mapping. (b) The Lasso coefficient profiles of prognosis-related genes. (c) The partial likelihood deviance is plotted against log (λ). Kaplan–Meier plot of overall survival of patients is in the high-risk and low-risk groups in the train cohort (d) and test cohort (f). ROC curves for three-gene signatures in train cohort (e) and test cohort (g).

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