Research Article
Analysis of Multiple Vitamins Serum Levels and Disease-Related Factors in Children with Acute Leukemia
Table 1
Analysis of infection-related influencing factors in children with acute leukemia.
| | Indicators | | Infected group (n = 52) | Noninfected group (n = 55) | t/X2 | value |
| | Age | | 7.54 ± 8.83 | 8.96 ± 16.95 | 0.901 | 0.370 | | BMI | | 16.88 ± 2.89 | 16.15 ± 2.76 | 1.335 | 0.100 | | Gender | Male | 31 (59.6) | 30 (54.5) | 0.280 | 0.596 | | Female | 21 (40.4) | 25 (45.5) | | Diagnostic results | ALL | 42 (80.8) | 42 (76.4) | 0.307 | 0.579 | | AML | 10 (19.2) | 13 (23.6) | | Immunophenotype | AML | 9 (17.3) | 13 (23.6) | 3.028 | 0.220 | | B | 38 (73.1) | 38 (69.1) | | T | 5 (9.6) | 4 (7.3) | | Liver function (missing = 1) | Abnormal | 17 (32.7) | 12 (22.22) | 1.461 | 0.227 | | Normal | 35 (67.3) | 42 (77.78) | | Kidney function | Abnormal | 12(23.1) | 7 (12.7) | 1.960 | 0.161 | | Normal | 40 (76.9) | 48 (87.3) | | Icterus | Yes | 2 (3.8) | 6 (10.9) | 1.928 | 0.165 | | No | 50 (96.2) | 49 (89.1) | | Biochemical indicators | Alanine aminotransferase (ALT, mmol/L) | 39.94 ± 92.14 | 38.38 ± 48.86 | 0.109 | 0.913 | | Aspartate aminotransferase (AST, mmol/L) | 39.02 ± 47.12 | 31.46 ± 23.50 | 1.049 | 0.297 | | Lactate dehydrogenase (LD, U/L) | 661.63 ± 1371.89 | 223.91 ± 65.42 | 2.364 | 0.020 | | Hydroxybutyric dehydrogenase (HBDH, U/L) | 474.55 ± 906.57 | 168.80 ± 50.27 | 2.498 | 0.014 | | Blood routine and serological parameters | White blood count (WBC, 109/L) | 14.99 ± 24.83 | 4.30 ± 4.53 | 3.139 | 0.002 | | Neutrophils (N, 109/L) | 3.66 ± 6.24 | 2.32 ± 2.19 | 1.489 | 0.140 | | Hemoglobin (Hb, g/L) | 80.17 ± 16.49 | 100.53 ± 20.85 | 5.581 | <0.001 | | Platelet count (PLT, 109/L) | 108.46 ± 94.2 | 209.11 ± 112.59 | 5.000 | <0.001 | | Lymphocyte (L, 109/L) | 7.57 ± 15.34 | 1.46 ± 2.16 | 2.928 | 0.004 | | C-reactive protein (CRP, mg/L) | 13.87 ± 27.82 | 2.40 ± 8.59 | 2.361 | 0.020 | | Activated partial thromboplastin time (APTT, s) | 29.22 ± 5.38 | 31.61 ± 7.16 | 1.930 | 0.056 | | Troponin (Tn) | 7.36 ± 9.68 | 6.49 ± 7.82 | 0.430 | 0.668 | | Vitamin level | Vitamin A (VA, μmol/L) | 0.73 ± 0.26 | 0.74 ± 0.18 | 0.400 | 0.690 | | Vitamin B1 (VB1, nmol/L) | 98.47 ± 11.71 | 100.05 ± 13.05 | 0.660 | 0.511 | | Vitamin B2 (VB2, μg/L) | 5.45 ± 1.94 | 5.71 ± 1.75 | 0.732 | 0.466 | | Vitamin B6 (VB6, nmol/L) | 33.85 ± 14.54 | 33.80 ± 15.4 | 0.016 | 0.987 | | Vitamin B9 (VB9, nmol/L) | 20.19 ± 5.83 | 19.38 ± 5.76 | 0.723 | 0.471 | | Vitamin B12 (VB12, pg/mL) | 485.32 ± 102.97 | 472.17 ± 79.12 | 0.738 | 0.462 | | Vitamin C (VC, μmol/L) | 39.22 ± 6.47 | 38.43 ± 4.54 | 0.728 | 0.469 | | Vitamin D (VD, nmol/L) | 37.96 ± 14.78 | 45.67 ± 19.97 | 2.259 | 0.026 | | Vitamin E (VE, μg/mL) | 10.76 ± 0.90 | 10.62 ± 0.56 | 0.956 | 0.341 |
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Data were mean ± SD or n (%). . AML, acute myeloid leukemia; BMI, body mass index. |
