Research Article
Analysis of Multiple Vitamins Serum Levels and Disease-Related Factors in Children with Acute Leukemia
Table 3
Analysis of the factors influencing progression of acute leukemia in children.
| | Indicators | | Treatment remission group (n = 56) | Nonremission group (n = 51) | t/X2 | |
| | Age | | 6.32 ± 3.72 | 5.66 ± 3.40 | 0.955 | 0.342 | | BMI | | 16.02 ± 2.51 | 17.03 ± 3.09 | 1.848 | 0.060 | | Gender | Male | 31 (55.4) | 30 (58.8) | 0.131 | 0.718 | | Female | 25 (44.6) | 21 (41.2) | | Diagnostic results | ALL | 49 (87.5) | 35 (68.6) | 5.966 | 0.010 | | AML | 7 (12.5) | 16 (31.4) | | Immunophenotype | AML | 7 (12.5) | 15 (29.4) | 6.309 | 0.043 | | B | 42 (75.0) | 34 (66.7) | | T | 7 (12.5) | 2 (3.9) | | Liver function | Abnormal | 20 (36.4) | 9 (17.6) | 4.664 | 0.030 | | Kidney function | Normal | 36 (63.6) | 42 (82.4) | | Icterus | Abnormal | 13 (23.2) | 6 (11.8) | 2.396 | 0.122 | | Normal | 43 (76.8) | 45 (88.2) | | Liver function (missing = 1) | Yes | 4 (7.1) | 4 (7.8) | 0.019 | 0.890 | | No | 52 (92.9) | 47 (92.2) | | Infection | Yes | 18 (32.1) | 34 (66.7) | 12.735 | <0.001 | | No | 38 (67.9) | 17 (33.3) | | Biochemical indicators | Alanine aminotransferase (ALT, mmol/L) | 42.93 ± 51.65 | 34.24 ± 90.83 | 0.610 | 0.543 | | Aspartate aminotransferase (AST, mmol/L) | 39.93 ± 40.17 | 29.50 ± 32.30 | 1.457 | 0.148 | | Lactate dehydrogenase (LD, U/L) | 231.11 ± 80.66 | 656.14 ± 1373.01 | 2.207 | 0.032 | | Hydroxybutyric dehydrogenase (HBDH, U/L) | 170.00 ± 59.74 | 475.02 ± 906.01 | 2.399 | 0.200 | | Serological indicators | White blood cell count (WBC, 109/L) | 4.16 ± 3.50 | 15.34 ± 25.14 | 3.149 | 0.003 | | Neutrophils (N, 109/L) | 2.73 ± 2.50 | 3.24 ± 6.24 | 0.547 | 0.587 | | Hemoglobin (Hb, g/L) | 99.79 ± 20.05 | 80.59 ± 18.14 | 5.175 | <0.001 | | Platelet count (PLT) | 183.00 ± 102.30 | 135.16 ± 124.19 | 2.182 | 0.031 | | (PLT, 109/L) | Lymphocyte (L, 109/L | 1.05 ± 1.16 | 8.14 ± 15.39 | 3.286 | 0.002 | | C-reactive protein (CRP, mg/L) | 7.14 ± 15.54 | 8.89 ± 25.93 | 0.426 | 0.671 | | Activated partial thromboplastin time (APTT, s) | 32.76 ± 7.29 | 28.03 ± 4.24 | 4.118 | <0.001 | | Troponin (Tn) | 9.24 ± 10.03 | 5.20 ± 5.33 | 2.533 | 0.01 | | Vitamin level | Vitamin A (VA, μmol/L) | 0.74 ± 0.18 | 0.73 ± 0.26 | 0.141 | 0.888 | | Vitamin B1 (VB1, nmol/L) | 102.58 ± 12.53 | 95.67 ± 11.27 | 3.003 | 0.003 | | Vitamin B2 (VB2, μg/L) | 5.72 ± 1.81 | 5.44 ± 1.88 | 0.793 | 0.430 | | Vitamin B6 (VB6, nmol/L | 30.41 ± 13.29 | 37.58 ± 15.81 | 2.547 | 0.012 | | Vitamin B9 (VB9, nmol/L | 20.55 ± 5.78 | 18.92 ± 5.71 | 1.468 | 0.145 | | Vitamin B12 (VB12, pg/mL | 453.54 ± 73.62 | 506.03 ± 101.17 | 3.043 | 0.003 | | Vitamin C (VC, μmol/L | 39.57 ± 5.77 | 37.99 ± 5.23 | 1.482 | 0.141 | | Vitamin D (VD, nmol/L | 44.93 ± 20.64 | 38.63 ± 13.98 | 1.828 | 0.070 | | Vitamin E (VE, μg/mL) | 10.69 ± 0.75 | 10.70 ± 0.75 | 0.057 | 0.955 |
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Data were mean ± SD or n (%). . AML, acute myeloid leukemia; BMI, body mass index. |
